On-loan Irish striker Evan Ferguson pounced on a parried shot to poke the ball home and make it 3-0 just past the half-hour mark.
Jeff Ekhator got a late consolation goal for Genoa with a deflected shot.
Roma had been at risk of falling out of touch with the leading pack after only one win in its last four games.
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The result lifts Gian Piero Gasperini’s side to 33 points, one point behind Napoli, two behind AC Milan and three behind leader Inter, although all three have a game in hand.
Genoa, meanwhile, remains 17th in the 20-team league and just two points above the relegation zone after its third loss in a row.
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Keep the discussion civilized. Absolutely NO personal attacks or insults directed toward writers, nor others who make comments.
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PLEASE TURN OFF YOUR CAPS LOCK.
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