A planned 55-hour closure of eastbound lanes on Interstate Highway 80 in San Francisco between 17th and Fourth streets will start Friday and last through the weekend, with the expectation that it will cause major travel delays for drivers.

Critical maintenance work along a 1.6-mile stretch of I-80 starting at 11 p.m. Friday through 6 a.m. Monday will address regular wear-and-tear from the millions of cars that make use of one of San Francisco’s busiest freeways.

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