CHICAGO -- Matt Cain and three relievers combined on a two-hitter, Buster Posey homered and the NL West-leading San Francisco Giants beat Carlos Zambrano and the Chicago Cubs 1-0 on Tuesday.

Cain and Zambrano each pitched six scoreless innings, but the Giants did just enough to prevail. Leading San Diego by a half-game and Colorado by 1 1/2 when the night began, San Francisco finally broke through with one out in the eighth when Posey drove a 3-1 pitch from Andrew Cashner (2-6) to center field, pumping his fist as he rounded the bases.

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