JUNEAU, Alaska (AP) — Republican Sen. Lisa Murkowski of Alaska announced Friday that she will run for reelection in 2022, setting up a race against a primary challenger endorsed by former President Donald Trump.

Playing up her centrist bona fides, Murkowski said in a campaign video that she would work across party lines to help Alaska and "stand up to any politician or special interest that threatens our way of life." Trump has vowed revenge against Murkowski and other Republican lawmakers who supported his impeachment over the Jan. 6 insurrection.

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