Suarez (3-3) struck out five and walked three in 6 2/3 innings. His no-hit bid ended with Josh Naylor's one-out double in the seventh.
The 30-year-old lefty earned his first win since April 27 against Toronto.
Caleb Durbin put the Red Sox ahead with a second-inning solo homer, his fifth of the year. Durbin had his second three-hit game this season, with his first coming against Tampa Bay on June 10.
Ceddanne Rafaela scored on a wild pitch in the seventh, and Marcelo Mayer drove in two more runs with a bases-loaded single.
Carlos Narváez added a sacrifice fly before Seattle finally escaped the inning on a diving catch by Dominic Canzone in right field.
Suarez issued a two-out walk that loaded the bases in the seventh on his final pitch of the night, but Justin Slaten ended the threat by striking out pinch-hitter J.P. Crawford to preserve a 5-0 lead.
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Mayer added one more insurance run with a ninth-inning RBI double. The Mariners got on the board thanks to Julio Rodríguez's two-run homer in the ninth.
Seattle starter Bryce Miller (3-1) struck out seven in five innings. He allowed three hits and one run.
Luis Castillo, who has started in all but three of his 258 career appearances, gave up five runs in four innings of relief as the Mariners revived their “piggyback” rotation.
Up next
Red Sox LHP Connelly Early (5-5, 3.81 ERA) starts opposite Mariners RHP Emerson Hancock (5-3, 3.28) on Saturday night.
Copyright 2026 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed without permission.
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Keep the discussion civilized. Absolutely NO personal attacks or insults directed toward writers, nor others who make comments.
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