The ChatGPT app icon on a smartphone in this photo illustration taken Oct. 27, 2025.Â
The OpenAI Foundation announced a $100 million grant for Alzheimer’s research earlier this week, in partnership with two Bay Area-based research institutes.
The foundation, which operates as the nonprofit arm of OpenAI, will collaborate with six organizations, including the University of California, San Francisco, and Palo Alto-based research nonprofit Arc Institute.
In a news release, the OpenAI Foundation said that since 1960, the mortality rate has fallen for cardiovascular disease, infectious disease, and cancer, but has risen slightly for Alzheimer’s.
Effective treatments remain elusive because multiple factors, like genetics, aberrations in the structure of proteins, inflammation, and neurological dysfunction, cause the disease.
As part of the research program, the Arc Institute will conduct experiments to understand how different health risk factors interact with each other to cause Alzheimer’s. The data collected from multiple iterations of such experiments will then be used to train AI models to arrive at the most likely effective interventions.
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