A large explosion struck central Tehran on Friday near a site where thousands of Iranians had gathered for an annual state-organized rally backing Palestinians and calling for Israel’s destruction. Israel had warned it would target the area. There were no immediate reports of casualties.

The blast came nearly two weeks into the widening war. Iran has continued missile and drone attacks on Israel and Gulf states and has effectively closed the Strait of Hormuz, a key route for about a fifth of the world’s traded oil, even as U.S. and Israeli aircraft strike targets across Iran.

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