AP News in Brief at 6:04 a.m. EDT

Hope that the two-month conflict could soon end buoyed international markets on Thursday, even as the U.S. military fired on an Iranian oil tanker attempting to breach an American blockade of Iran’s ports hours earlier. The developments followed days of mixed messaging from the Trump administration over its strategy to end the war.

Trump posted on social media that the two-month war could soon end and that oil and natural gas shipments disrupted by the conflict could restart. But he said that depends on Iran accepting a reported agreement that he did not detail.

“If they don’t agree, the bombing starts,” Trump wrote.

A fragile ceasefir e between the U.S. and Iran has largely held since April 8. But in-person talks between the two countries hosted by Pakistan last month failed to reach an agreement. The war began Feb. 28, when the U.S. and Israel launched strikes against Iran.

Russia says Ukraine launched a major drone attack after Moscow shunned ceasefire offer

Russian air defenses shot down 347 Ukrainian drones overnight, Russia’s Defense Ministry said Thursday, in what appeared to be a major attack after Moscow spurned Kyiv’s ceasefire earlier in the week and tension mounted over Russia's upcoming Victory Day celebrations.

Incoming drones were destroyed over 20 Russian regions, including Moscow, according to the Defense Ministry, in Ukraine’s second-biggest aerial attack since Russia’s all-out invasion more than four years ago. The largest was last March when it launched 389 drones.

The attack came ahead of Russia’s most important secular holiday, when it marks the anniversary of the defeat of Nazi Germany in World War II. Russian authorities have declared a unilateral ceasefire in Ukraine for Friday and Saturday.

Ukraine had responded to that with its own suspension of hostilities from midnight Tuesday. But Ukrainian President Volodymyr Zelenskyy said Moscow disregarded the goodwill gesture and launched fresh attacks.

“Russia has not stopped any type of its military activity. Unfortunately, it has not stopped. Ukraine will act symmetrically,” Zelenskyy said in his regular evening video address Wednesday.

Cruise ship with hantavirus outbreak heads to Canary Islands after 3 are evacuated

PRAIA, Cape Verde (AP) — Two patients with hantavirus and one suspected of infection were evacuated Wednesday from a cruise ship at the center of a deadly outbreak, the U.N. health agency said. The ship then departed Cape Verde with nearly 150 people on board — isolated in their cabins — and headed to Spain’s Canary Islands.

Associated Press footage showed health workers in protective gear evacuating three patients. Two arrived at Amsterdam's airport Wednesday evening and were taken to separate hospitals.

Three people have died, and one body remained on the ship, the World Health Organization said. Of eight recorded cases, five were confirmed by laboratory testing.

Hantavirus usually spreads by inhaling contaminated rodent droppings and can spread person-to-person, though that is rare, according to the WHO, whose top epidemic expert said the risk to the public is low.

Health officials in Europe and Africa are trying to identify people who may have had contact with people who earlier left the ship, which departed April 1 from South America for stops in Antarctica and several remote Atlantic islands.

Hantavirus is on the rise in Argentina, where a stricken cruise ship began its journey

BUENOS AIRES, Argentina (AP) — Officials and experts in Argentina are scrambling to determine if their country is the source of a deadly hantavirus outbreak that has gripped an Atlantic cruise.

The health emergency aboard the ship that's moored across the ocean comes as Argentina sees a surge of hantavirus cases that many local public health researchers attribute to the recently accelerating effects of climate change. Argentina, where the cruise to Antarctica departed, is consistently ranked by the World Health Organization as having the highest incidence of the rare, rodent-borne disease in Latin America.

Higher temperatures expand the virus’ range because, in part, as it gets warmer and ecosystems change, rodents that carry the hantavirus can thrive in more places, experts say. People typically contract the virus from exposure to rodent droppings, urine or saliva.

“Argentina has become more tropical because of climate change, and that has brought disruptions, like dengue and yellow fever, but also new tropical plants that produce seeds for mice to proliferate,” said Hugo Pizzi, a prominent Argentine infectious disease specialist. “There is no doubt that as time goes by, the hantavirus is spreading more and more.”

The Argentine Health Ministry on Tuesday reported 101 hantavirus infections since June 2025, roughly double the caseload recorded over the same period the previous year.

Judge releases note cellmate says he found after Epstein’s suspected suicide attempt

NEW YORK (AP) — A note Jeffrey Epstein’s former cellmate claimed he found after the millionaire sex offender’s first suspected jail suicide attempt was made public Wednesday, years after being sealed and locked in a courthouse vault as part of an unrelated legal dispute.

U.S. District Judge Kenneth Karas in White Plains, New York, ordered the release of the note after The New York Times asked him last week to unseal it and other documents in a case involving the former cellmate, Nicholas Tartaglione. Federal prosecutors did not oppose the request.

Few people had known about the note until Tartaglione, a former police officer serving a life sentence for killing four people, mentioned it last year on writer Jessica Reed Kraus’ podcast.

Tartaglione claimed he discovered the note in a book after Epstein was found on the floor of their cell at a Manhattan federal jail on July 23, 2019, with a strip of bedsheet around the financier's neck. That was about three weeks before Epstein was found dead in his cell in what authorities concluded was a suicide.

“They investigated me for month -- found nothing!!!” said the short note, which is hard to decipher in some places. “It is a treat to be able to choose” the “time to say goodbye," the note continues. “Watcha want me to do -- Bust out cryin!!”

Tennessee poised to vote on new US House map sought by Trump that carves up Memphis

NASHVILLE, Tenn. (AP) — Republican lawmakers in Tennessee are poised to take up a plan Thursday that could carve up a majority-Black congressional district, reshaping it to the GOP's advantage as part of President Donald Trump's strategy to try to hold on to a slim House majority in the November midterm elections.

The redistricting effort in Tennessee is one of several rapidly advancing plans in Southern states as Republicans try to leverage a U.S. Supreme Court ruling that weakened the federal Voting Rights Act.

The court ruled that Louisiana relied too heavily on race when creating a second Black-majority House district as it attempted to comply with the federal law. The high court's decision altered a decades-old understanding of the law, giving Republicans grounds to try to eliminate majority-Black districts that have elected Democrats.

Louisiana has postponed its congressional primary to give time for state lawmakers to craft a new House map. Legislation awaiting a final vote in Alabama also would upend the state’s congressional primaries if courts allow the state to change its U.S. House districts. In South Carolina, meanwhile, Republican lawmakers urged on by Trump have taken initial steps to add congressional redistricting to their agenda.

The states are the latest to join an already fierce national redistricting battle. Since Trump prodded Texas to redraw its U.S. House districts last year, eight states have adopted new congressional districts. From that, Republicans think they could gain as many as 13 seats while Democrats think they could gain up to 10. But some competitive races mean the parties may not get everything they sought in the November elections.

Hopes for reopening the Strait of Hormuz push world shares higher, as Brent crude holds above $100

World shares jumped on Thursday, with Tokyo's Nikkei 225 gaining almost 6% to a new record as investors waited to see if the U.S. and Iran will strike a deal allowing tankers to deliver crude from the Persian Gulf again.

Japan's benchmark Nikkei 225 index jumped more than 3,300 points to 63,086.00 as markets in Tokyo reopened following “Golden Week” holidays.

In early European trading, Germany’s DAX edged 0.2% higher to 24,988.08 and the CAC 40 in Paris was up 0.3% at 8,325.55. Britain's FTSE 100 slipped 0.3% to 10,411.19.

The future for the S&P 500 was up 0.1% while that for the Dow Jones Industrial Average climbed 0.3%.

Japan's Nikkei 225 has gained nearly 20% in the past three months and more than 70% in the past year, pushed higher by strong buying of tech shares that have benefited from the boom in artificial intelligence.

Polls open in UK local elections seen as a verdict on Keir Starmer's leadership

LONDON (AP) — British voters cast ballots Thursday in local and regional elections that could shake up the country's politics and deliver a heavy blow to embattled Prime Minister Keir Starmer.

Starmer’s center-left Labour Party is bracing for big losses in polls that will choose about 5,000 local councilors and a handful of mayors across England, as well as semiautonomous parliaments in Scotland and Wales.

Polls opened at 7 a.m. and will close at 10 p.m. (2100 GMT). Some local authorities will count ballots overnight, but the bulk of the results are likely to be declared on Friday afternoon.

Local elections usually focus on issues like garbage collection, graffiti and potholes, but Starmer’s opponents have painted Thursday's vote as a midterm referendum on the prime minister.

A rout could trigger moves by restive Labour lawmakers to oust a leader who led them to power less than two years ago. Even if Starmer survives for now, many analysts doubt he will lead the party into the next national election, which must be held by 2029.

Rubio arrives for audience with Pope Leo XIV to ease tensions after Trump's criticism over Iran

VATICAN CITY (AP) — U.S. Secretary of State Marco Rubio opened a fence-mending visit to the Vatican on Thursday after President Donald Trump’s broadsides against Pope Leo XIV and the U.S.-Israeli war in Iran angered the Holy See and sparked ongoing sparring between the two American leaders.

Rubio, a practicing Catholic, had an audience scheduled with Leo, which was complicated at the last minute by Trump’s latest criticism of the Chicago-born pope. Leo has pushed back, calling out Trump’s misrepresentations of his views on Iran and nuclear weapons and insisting that he is merely preaching the biblical message of peace.

Rubio was also due to meet with the Vatican secretary of state, Cardinal Pietro Parolin, who on the eve of his visit strongly defended Leo and criticized Trump’s attacks in understated diplomatic terms. “Attacking him like that or criticizing what he does seems a bit strange to me, to say the least,” Parolin said Wednesday.

Parolin said Washington had requested Rubio's audience, and that the pope was open to continued dialogue.

“We cannot ignore the United States," Parolin said. "Despite some difficulties, they certainly remain a key partner for the Holy See, not least because they play a role in almost every situation we face today.”

Russia is ramping up its attempts to kill opponents in Europe, intelligence officials say

When Vladimir Osechkin wants to take his children to school or go to the supermarket, he calls the police.

The Russian activist has lived under protection since 2022 because French officials believe Russia is trying to kill him.

In April 2025, a crew of Russian men staked out Osechkin's home and the surrounding area in southwestern France for several hours, taking videos and photos in suspected groundwork for an assassination, according to court documents seen by The Associated Press that are not public. Several years earlier, Osechkin said, a red dot — which he thought was a laser sight for a gun — appeared on his wall.

Elsewhere in Europe, Lithuanian officials disrupted a plot last year to kill a Lithuanian supporter of Ukraine and another against a Russian activist. Officials in Germany have similarly broken up two plots: one to target the head of a German weapons company supplying Ukraine, the other against a Ukrainian military official. Polish authorities arrested a man in 2024 in what they said was a plot to assassinate Ukrainian President Volodymyr Zelenskyy. And that same year, a Russian helicopter pilot who defected was killed in Spain — with Russian operatives the prime suspects.

While Russian officials have long been accused of silencing the country’s enemies abroad, three Western intelligence officials from different countries told AP that a campaign of targeted killings has ramped up since President Vladimir Putin's 2022 invasion of Ukraine.