AP News in Brief at 12:04 a.m. EDT

The taking of Beaufort castle, near the city of Nabatiyeh, followed days of airstrikes and intense fighting in nearby villages between Israeli troops and Hezbollah militants.

The capture marked a major Israeli advance in the latest Israel-Hezbollah war, which began on March 2, when Hezbollah fired rockets into northern Israel two days after the U.S. and Israel attacked its main backer, Iran.

Since then, Israel has launched a ground invasion, capturing dozens of Lebanese villages and towns close to the border. Hezbollah has launched thousands of missiles and drones at Israeli soldiers in southern Lebanon and northern Israel.

The Israeli push came despite a nominal ceasefire that has been in place since April 17 and just days before Lebanon and Israeli hold their next round of direct talks in Washington starting Tuesday.

What to know as Israeli forces' historic Lebanon incursion complicates an Iran deal

TEL AVIV, Israel (AP) — Israeli forces are making their deepest incursion inside Lebanon since they withdrew from the country over a quarter-century ago, despite a nominal U.S.-brokered ceasefire and the first direct talks between the countries in decades.

The Israeli advance presents a challenge in the emerging deal to extend the Iran war ceasefire as Tehran wants any agreement to end fighting in Lebanon, too. Qatar called it a “dangerous escalation." Germany's foreign minister said it was cause for serious concern, according to German press agency dpa. There was no comment by the United States.

On Sunday, Israeli forces seized a symbolic fort in southern Lebanon that offers commanding views across Lebanon and into northern Israel. The last time they seized it, they held it for 18 years.

Israel says it is targeting the Iranian-backed Hezbollah militant group, which has a strong political presence in southern Lebanon and has launched thousands of missiles and drones at Israeli soldiers there and in northern Israel.

Israel has warned Lebanese civilians across the south to evacuate or risk being in the line of fire. Lebanese Prime Minister Nawaf Salam on Saturday accused Israel of “implementing a policy of total destruction of cities and towns.”

Pro-Trump candidate pulls ahead in Colombia presidential vote as ruling party sows doubt in results

BOGOTÁ, Colombia (AP) — Tough-on-crime outsider Aberaldo de la Espriella took the lead in Colombia's presidential race in the first round of voting Sunday night, setting up a runoff with Iván Cepeda, an ally of Colombia’s outgoing President Gustavo Petro who questioned the results of the election.

With no candidate taking an outright majority of the vote, the election will head to a second round in June.

But Cepeda and Petro sowed doubt in the results of the first round, claiming without evidence that hundreds of thousands of votes were manipulated and that foreign actors manipulated the results of the election.

Cepeda said he was waiting for electoral authorities to scrutinize the results before accepting the election.

“Only when the vote-counting commissions have fully clarified what happened will we comment on tonight’s results,” Cepeda said, though he acknowledged the vote was likely going to a second round.

Platner's wife calls news coverage of Senate hopeful's sexually explicit texts with women 'shameful'

Graham Platner’s wife called the media reports that her husband had previously exchanged sexually explicit text messages with several women “shameful" over the weekend, the latest controversy to hit the Maine Democrat’s whirlwind Senate campaign.

Platner, an oyster farmer and combat veteran, posted a video taken by his wife, Amy Gertner, who reportedly told his campaign of the text messages last year. In the five-minute video, Gertner avoided speaking directly about her husband's reported texts, dubbing the broader coverage as “gossip" and saying that “being married is hard.”

“I find it really shameful that there’s a group of media outlets and people who are willing to spread gossip,” she said in the informal, selfie-style video where she walked along a road. “No marriage is perfect, and I don't want a perfect marriage. I want my marriage.”

Platner is seeking the Democratic nomination for one of the most closely watched Senate races as Democrats hope to defeat longtime Republican Sen. Susan Collins in the party's efforts to win control of the narrowly divided Senate. The Maine primary is June 9.

Genevieve McDonald, a then-campaign staffer for Platner, told the The Associated Press that the candidate was “sexting multiple women while married" and that “the campaign tried to assess that as an election vulnerability.”

Ukraine hits Russian energy targets and denies striking Kremlin-occupied nuclear plant

KYIV, Ukraine (AP) — Kyiv on Sunday launched new strikes overnight on Russian energy sites. It has also denied Moscow’s claims that a Ukrainian drone struck the Russian-controlled Zaporizhzhia nuclear plant.

Ukraine’s General Staff said Ukrainian drones struck the Saratov oil refinery in southwestern Russia, causing a large-scale fire. It claimed the refinery has been supplying Moscow’s war effort.

The refinery belongs to Russia’s state oil enterprise, Rosneft. Local Russian Gov. Roman Busargin said Ukrainian drones had damaged civilian infrastructure, but did not give details. Astra, an independent Russian news channel, said an oil refinery was on fire in the city of Saratov.

Ukraine has stepped up its attacks on Russia’s oil and gas facilities in recent months, arguing the energy sector funds and directly fuels Moscow’s more than four-year invasion.

“Tonight, our soldiers applied Ukraine’s long-range sanctions against an oil refinery in Saratov, Russia — approximately 700 kilometers (435 miles) from the front line. A significant achievement,” Ukrainian President Volodymyr Zelenskyy wrote on social media on Sunday.

French capital hosts Paris Saint-Germain parade after clashes marred Champions League win

PARIS (AP) — A huge crowd of supporters gathered peacefully near the Eiffel Tower on Sunday to celebrate Paris Saint-Germain's second Champions League title victory, which was marred by violent clashes overnight across France and led police to detain hundreds of people.

Interior Minister Laurent Nuñez said 780 people were detained in Paris and other cities and 57 officers were wounded, with most suffering minor injuries, as football fans set off fires and vandalized shops overnight.

Nuñez said at a news conference on Sunday that “the situation has been largely brought under control."

“Most of the celebrations took place peacefully” across the French capital, he said, noting most incidents happened in the Champs Elysees neighborhood and close to the Parc des Princes stadium, in western Paris, where fans had gathered to watch the match.

Fans began celebrating in Paris after the final whistle on Saturday night in Budapest, Hungary, where Paris Saint-Germain was crowned Champions League winners after beating Arsenal in a dramatic penalty shootout. Fans marched along the avenues near Paris’ Arc de Triomphe monument, with some setting off flares and blaring car horns. Around 20,000 people gathered on the Champs-Elysees, where police worked to contain the crowd.

Blast at building storing explosives in Myanmar kills more than 45 people

BANGKOK (AP) — A blast on Sunday at a building in northeastern Myanmar said to have been storing explosives for mining has killed more than 45 people, according to rescue workers and independent media reports.

About 70 other people were injured in the explosion that took place around noon in the village of Kaungtup, in Namhkam township.

The area, located about 3 kilometers (2 miles) south of the Chinese border, is under the control of the Ta’ang National Liberation Army, an ethnic armed group which has engaged in sporadic fighting against Myanmar’s central government.

A rescue worker who rushed to the site of the blast told The Associated Press that 46 bodies, including six children, had been recovered by Sunday evening and taken for cremation.

The rescuer, who spoke on condition of anonymity for security reasons, said 74 injured people had been transported to the township hospital and rescue operations were continuing.

Man charged with murder in killings of 3 on Hawaii's Big Island

HONOLULU (AP) — Authorities in Hawaii have charged a 36-year-old man with murder in the killings of three people in a remote community known for its eclectic, communal lifestyle.

Jacob Daniel Baker was charged with counts of first- and second-degree murder Saturday, the Hawaii Police Department said in a news release.

Baker remained jailed without bond Sunday and police said his first court appearance was scheduled for Monday. It was not immediately known if Baker had an attorney who could speak for him.

Charges in the killings came two days after police apprehended Baker following a manhunt on Hawaii's Big Island, where the three victims were found in the rural Puna community known for its tropical landscape and free-spirited residents.

Robert Shine, 69, was found dead Monday partially submerged in a cement pond, according to police. The second victim, a 79-year-old man, was discovered Tuesday a few hundred feet away. Friends identified him as Chitta Morse.

Experimental pill promises new hope for deadly pancreatic cancer

WASHINGTON (AP) — A novel pill helped people with advanced pancreatic cancer live longer, researchers reported Sunday, raising hopes of long-needed better treatments for one of the deadliest types of cancer.

“While not curing the cancer, it is a very large step forward,” said Dr. Zev Wainberg, of the University of California, Los Angeles, who helped lead the study.

The drug is called daraxonrasib and it blocks a mutated protein that fuels tumor growth in more than 90% of pancreatic cancer cases — a target that had eluded treatment for decades.

The daily pills nearly doubled survival time, with fewer severe side effects, in a study that randomly assigned the experimental drug or more chemotherapy to 500 patients whose metastatic, or spreading, cancer had quit responding to prior treatment. The findings were published in the New England Journal of Medicine and presented Sunday at the American Society for Clinical Oncology meeting in Chicago.

Those taking daraxonrasib lived for a median of 13.2 months compared with 6.7 months for chemotherapy recipients. While that may seem like a small improvement, Wainberg said it marked the first drug to show a substantial advantage over chemotherapy.

As the Pentagon pushes for battlefield AI, some military leaders urge caution

TAMPA, Fla. (AP) — The Trump administration is pushing to unleash the power of artificial intelligence for the U.S. military while facing calls to put up guardrails around the rapidly developing technology from some companies — and even notes of caution from top leaders in uniform.

Adm. Frank Bradley, head of U.S. Special Operations Command, told attendees of a recent annual special forces conference in Tampa, Florida, that troops “have to be very careful about how we come to (AI’s) employment and its inspiration into the delivery of lethality.”

Bradley said he can see a future where AI determines what targets to hit but that “we, as humans, have to have the confidence that ... it's going to deliver violence only where we intend it to be delivered.”

The remarks from Bradley, who oversees the units that handle the military’s most difficult and dangerous operations, about the need to ensure safeguards come as his boss, Defense Secretary Pete Hegseth, is pushing to rapidly evolve the military through AI. It is a push that has led to clashes with some tech companies worried about safety measures.

Hegseth has insisted that the Pentagon be allowed to use the technology any legal way it sees fit. He told an audience of SpaceX employees in January he would reject any AI models “that won’t allow you to fight wars” and that his vision for the technology was systems that operate “without ideological constraints that limit lawful military applications.”